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St.John's Wort for Bipolar Affective Disorder?

Question:
I was speaking to someone recently who told me about someone he knew whom he described as manic-depressive but who was not seeing a shrink about it. Instead he described the individual in question as self-adminstering St.John's Wort to control the condition. Since I know nothing about this subject, I would like to know whether St.John's Wort can in fact be used to treat manic-depression and, if so, what is the active principle that makes this possible?


Answer:
Bipolar disorder is so serious, I wouldn't play games with it. Antidepressants are sometimes given for BPD, when the person is intolerant to lithium, or does not respond to it. But this is done under a psychiatrist's care, with lots of feedback so s/he can know they are getting it right. Antidepressants do not treat the manic stage. Quite often, if a person likes his manic stage and does not take his meds until the last minute before the crash, he guesses wrong, is too late, and then the lithium doesn't work during the depressive stage. read a good article in a Healthy Living Guide about St. John's wort written by Ronald Reichert, a naturopthaic doctor from Vancouver. This herb apparently works in ways similar to the three main classes of anti-depressants- MAOIs, tricyclics, and SSRIs- in that St. John's wort inhibits the brain uptake of serotonin, which we need to have floating around in the brain to feel un-depressed. The active ingredients might be hypericin, quercitrin and hyperforin.In a study done in Germany (from this same article) the herb worked as effectively as a regular anti-depressant in 45-50% of cases. I do know some people who have taken it and do feel it helps. It is recommended for mild to moderate cases of depression. Since I've seen the amazing things other herbs can do why knock Mother Nature, all our real cures are in her wonderful world. I'm sure there will be more studies into this herb.Even when an herb is shown to be effective, there is difficultyobtaining a controlled and consistent dosage. This makes synthesized versions of the active ingredients preferable. Even synthesized medications are part of mother nature since mother nature does not discriminate at the molecular level (which is where chemistry takes place).



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